教育工作经历

2020.08至今 365365最快线路检测中心

2013.09-2020.07  中国科学技术大学，理学博士，导师：梁高林教授

2009.09-2013.06  四川大学，理学学士
 

教学简介

科研简介

  围绕癌症等疾病的诊断与治疗进行纳米生物分析，分子与细胞成像，超分子化学相关的基础研究与应用研究。目前已发在Angew. Chem. Int. Ed., Adv. Funct. Mater., ACS Nano, Nano Lett.等期刊上发表论文多篇。

社会兼职

科研项目

3. 国家自然科学基金青年科学基金项目（22204021），2023-2025

2. 福建省自然科学基金面上项目（2022J01068），2022-2025

1. 福州大学科研启动经费 （511043），2021-2023

代表性论文

19. Qian Li ¹, Zhongxiang Chen ¹, Lichao Su, Ying Wu, Wei Du *, Jibin Song *. Constructing Turn-on Bioluminescent Probes for Real-time Imaging of Reactive Oxygen Species during Cisplatin Chemotherapy. Biosens. Bioelectron. 2022, 216, 114632.

18. Rongrong Wu,^§ Zhongxiang Chen,^§ Hongqi Huo,^§ Lanlan Chen,* Lichao Su, Xuan Zhang, Ying Wu, Zhicun Yao, Shenggan Xiao, Wei Du,* and Jibin Song*. Ratiometric Detection of H₂S in Liver Injury by Activated Two-Wavelength Photoacoustic Imaging. Anal. Chem. 2022, 94 (30), 10797−10804.

17. Meng Yuan, Xiao Fang, Ying Wu, Yuanji Xu*, Hongjuan Feng, Jing Mu*, Zhongxiang Chen, Yuhong Lin, Qinrui Fu, Wei Du, Huanghao Yang, and Jibin Song*. Activatable Nanoprobe with Aggregation-Induced Dual Fluorescence and Photoacoustic Signal Enhancement for Tumor Precision Imaging and Radiotherapy. Anal. Chem. 2022, 94(12), 5204–5211.

16. Rui Luo, Chunqing Ou, Xinchao Li, Yanfang Wang, Wei Du, Gaolin Liang*, and Changyang Gong*. An Acidity-Initiated Self-Assembly/Disassembly Nanoprobe to Switch on Fluorescence for Tumor-Targeted Near-Infrared Imaging. Nano Lett. 2022, 22(1), 151–156.

15. Chenchen Wang, Wei Du, Chenfan Wu, Shan Dan, Miao Sun, Tong Zhang, Bin Wang, Yue Yuan*, and Gaolin Liang*. Cathespin B-Initiated Cypate Nanoparticle Formation for Tumor Photoacoustic Imaging. Angew. Chem. Int. Ed. 2022, 61(5), e202114766.

14. Chengfan Wu, Rui Zhang, Wei Du, Liang Cheng,* and Gaolin Liang*. Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles. In book: Photoacoustic Probes for In Vivo Imaging. Methods in Enzymology 657:111-144. Edited by Jefferson Chan. Academic Press. 2021（book chapter）

13. Feicheng Bai^#, Wei Du^#, (co-first author)Xia Liu, Lichao Su, Zhi Li, Tao Chen, Xiaoguang Ge, Qingqing Li, Huanghao Yang, and Jibin Song*. A NO-Responsive Ratiometric Fluorescent Nanoprobe for Monitoring Drug-Induced Liver Injury in the Second Near-Infrared Window, Anal. Chem. 2021, 93(46), 15279–15287.

12. Hongjuan Feng,# Qinrui Fu,^# Wei Du, ^# (co-first author) Rong Zhu, Xiaoguang Ge, Chenlu Wang, Qingqing Li, Lichao Su, Huanghao Yang, and Jibin Song*. Quantitative Assessment of Copper(II) in Wilson’s Disease Based on Photoacoustic Imaging and Ratiometric Surface-Enhanced Raman Scattering. ACS Nano 2021, 15(2), 3402-3414.

11. Chenchen Wang,^|| Wei Du,^|| (co-first author) Tong Zhang, and  Gaolin Liang*. A Bioluminescent Probe for Simultaneously Imaging Esterase and Histone Deacetylase Activity in a Tumor. Anal. Chem. 2020, 92 (23), 15275-15279.

10. Jihua Chen,^# Yinchu Ma,^# Wei Du,^# (co-first author) Tianyue Dai, Yanfang Wang, Wei Jiang, Yifei Wan, Yucai Wang, Gaolin Liang*, and Guangfeng Wang*. Furin-Instructed Intracellular Gold Nanoparticle Aggregation for Tumor Photothermal Therapy. Adv. Funct. Mater. 2020, 30 (50), 2001566.

9. Yanfang Wang,^§ Wei Du,^§ (co-first author) Tong Zhang, Yu Zhu, Yanhan Ni, Chenchen Wang, Fatima Maria Sierra Raya, Liwei Zou, Longsheng Wang,* and Gaolin Liang*. A Self-evaluating photothermal therapeutic nanoparticle. ACS Nano 2020. A 14, 9585−9593.

8. Wei Du, Yuanyuan Chong, Xiaomu Hu, Yanfang Wang, Yu Zhu, Jihua Chen, Xiaoxia Li, Qun Zhang, Guangfeng Wang,* Jun Jiang,* and Gaolin Liang*. Increasing Photothermal Efficacy by Simultaneous Intra- and Intermolecular Fluorescence Quenching. Adv. Funct. Mater. 2020, 30 (5), 1908073.

7. Chengfan Wu, Rui Zhang, Wei Du, Liang Cheng,* and Gaolin Liang*. Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors. Nano Lett. 2018, 18(12), 7749-7754.

6. Wei Du, Xiaomu Hu, Weichen Wei, and Gaolin Liang*. Intracellular Peptide Self-Assembly: A Biomimetic Approach for in Situ Nano-drug Preparation. Bioconjugate Chem. 2018, 29(4), 826-837.

5. Ling Dong, Junchao Qian, Zijuan Hai, Jinyong Xu, Wei Du, Kai Zhong,* and Gaolin Liang*. Alkaline Phosphatase-Instructed Self-Assembly of Gadolinium Nanofibers for Enhanced T2-Weighted Magnetic Resonance Imaging of Tumor. Anal. Chem. 2017, 89(13), 6922-6925.

4. Wei Du, Yusi Cui and Gaolin Liang*. Applications of Organic-Inorganic Hybrid Nanoparticles for Cancer Imaging. In book: Hybrid Nanomaterials: Design, Synthesis, and Biomedical Applications, pp.110-155. Edited by Feng Chen and Weibo Cai. CRC press. 2016. （book chapter）

3. Yusi Cui, Wei Du, and Gaolin Liang*. Self-Assembly/Disassembly of Nanostructures Confers “Off/On” Signal for Molecular Imaging. ChemNanoMat 2016, 2(5) 344-353.

2. Wei Du, Yue Yuan, Lin Wang, Yusi Cui, Hui Wang, Huiqin Xu*, and Gaolin Liang*. Multifunctional Bioconjugate for Cancer Cell-Targeted Theranostics. Bioconjugate Chem., 2015, 26 (12), 2571-2578.

1. Yue Yuan, Lin Wang, Wei Du, Zhanling Ding, Jia Zhang, Tao Han, Linna An, Huafeng Zhang*, and Gaolin Liang*. Intracellular Self-Assembly of Taxol Nanoparticles for Overcoming Multi-Drug Resistance. Angew. Chem. Int. Ed. 2015, 54, 9700-9704.

获奖情况

其他

 本课题组招生方向：分析化学（学硕），生物与医药（专硕）